The pharmacodynamic effects of sildenafil in subjects with ED of broad-spectrum etiology have been evaluated in response to visual sexual stimulation and tactile stimulation, following doses of 10, 25, 50 and 100 mg, using penile plethysmography as an objective measure of penile rigidity (rigidity > 60% at the base of the penis).Mean sildenafil plasma concentrations measured after the administration of a single oral dose of 100 mg to healthy male volunteers is depicted below: Figure 1: Mean Sildenafil Plasma Concentrations in Healthy Male Volunteers. viagra kaufen.
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